Patrik Christen
Patrik Christen
Lecturer, FHNW, Institute for Information Systems, Switzerland
patrik.christen@fhnw.ch
External Lecturer, ETH Zurich, Switzerland
patrik.christen@hest.ethz.ch
Research
Teaching
Journal Articles
arXiv Automatic Programming of Cellular Automata and Artificial Neural Networks Guided by Philosophy.
P. Christen and O. Del Fabbro
arXiv, 1905.04232, 2019.
PLOSONE Virtual supersampling as post-processing step preserves the trabecular bone morphometry in human peripheral quantitative computed tomography scans.
F. A. Schulte, P. Christen, S. D. Badilatti, I. Parkinson, S. Khosla, J. Goldhahn, and R. Müller
PLoS ONE, 2019.
PM Moving beyond the genome with computer modelling.
P. Christen
Personalized Medicine 15(3):145-148, 2018.
JOR Patient-specific in silico models can quantify primary implant stability in elderly human bone.
J. A. Steiner, U. Hofmann, P. Christen, J. Favre, S. J. Ferguson, and G. H. van Lenthe.
Journal of Orthopaedic Research 36(3):954-962, 2018.
PLOSONE Least-detectable and age-related local in vivo bone remodelling assessed by time-lapse HR-pQCT.
P. Christen , S. Boutroy, R. Ellouz, R. Chapurlat, and B. van Rietbergen
PLoS ONE 13(1), 2018.
PLOSONE Feasibility of rigid 3D image registration of high-resolution peripheral quantitative computed tomography images of healing distal radius fractures.
J. J. A. de Jong, P. Christen, S. Boutroy, P. P. Geusens, J. P. W. van den Bergh, R. Müller, and B. van Rietbergen
PLoS ONE 12(7), 2017.
COR In vivo high-resolution computed tomography assessment of bone remodelling and its mechanoregulation.
P. Christen and R. Müller.
Current Osteoporosis Reports 15(4):311-317, 2017.
JOR A novel in silico method to quantify primary stability of screws in trabecular bone.
J. A. Steiner, P. Christen, R. Affentranger, S. J. Ferguson, and G. H. van Lenthe.
Journal of Orthopaedic Research 35(11):2415-2424, 2017.
JEM Computational modeling of long-term effects of prophylactic vertebroplasty on bone adaptation.
S. D. Badilatti, P. Christen, Stephen J. Ferguson, and R. Müller
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 231(5):423-431, 2017.
JBIOMECH Load-adaptive bone remodeling simulations reveal osteoporotic microstructural and mechanical changes in whole human vertebrae.
S. D. Badilatti, P. Christen, I. Parkinson, and R. Müller
Journal of Biomechanics 49(16):3770-3779, 2016.
CDBE Towards in silico prognosis using big data.
N. Ohs, F. Keller, O. Blank, W.-Y. W. Lee, C.-Y. J. Cheng, P. Arbenz, R. Müller, and P. Christen
Current Directions in Biomedical Engineering 2(1):57-60, 2016.
BMMB Large-scale microstructural simulation of load-adaptive bone remodeling in whole human vertebrae.
S. D. Badilatti, P. Christen, A. Levchuk, J. H. Marangalou, B. van Rietbergen, and R. Müller
Biomechanics and Modeling in Mechanobiology, 15(1):83-95, 2016.
JRSI Voxel size dependency, reproducibility, and sensitivity of an in vivo bone loading estimation algorithm.
P. Christen, F. A. Schulte, A. Zwahlen, B. van Rietbergen, S. Boutroy, L. J. Melton III, S. Amin, S. Khosla, J. Goldhahn, and R. Müller
Journal of The Royal Society Interface 13(114), doi:10.1098/rsif.2015.0991, 2016.
JANATOMY A potential mechanism for allometric trabecular bone scaling in terrestrial mammals.
P. Christen, K. Ito, and B. van Rietbergen.
Journal of Anatomy, 226(3):236-243, 2015.
NCOMMS Bone remodelling in humans is load-driven but not lazy.
P. Christen, K. Ito, R. Ellouz, S. Boutroy, E. Sornay-Rendu, R. D. Chapurlat, and B. van Rietbergen.
Nature Communications, 5:4855, doi:10.1038/ncomms5855, 2014.
BMMB Determination of hip-joint loading patterns of living and extinct mammals using an inverse Wolff's law approach.
P. Christen, K. Ito, F. Galis, and B. van Rietbergen.
Biomechanics and Modeling in Mechanobiology, 14(2):427-432, 2015.
BONE Challenges in longitudinal measurements with HR-pQCT: Evaluation of 3D registration method to improve bone microarchitecture and strength reproducibility.
R. Ellouz, R. Chapurlat, B. van Rietbergen, P. Christen, J. B. Pialat, and S. Boutroy.
Bone, 63:147-157, 2014.
JBIOMECH Validation of a bone loading estimation algorithm for patient-specific bone remodeling simulations.
P. Christen, K. Ito, A. A. Dos Santos, R. Müller, and B. van Rietbergen.
Journal of Biomechanics, 46(5):941-948, 2013.
JBIOMECH Subject-specific bone loading estimation in the human distal radius.
P. Christen, K. Ito, I. Knippels, R. Müller, G. H. van Lenthe, and B. van Rietbergen.
Journal of Biomechanics, 46(4):759-766, 2013.
JBIOMECH Patient-specific bone modelling and remodelling simulation of hypoparathyroidism based on human iliac crest biopsies.
P. Christen, K. Ito, R. Müller, M. R. Rubin, D. W. Dempster, J. P. Bilezikian, and B. van Rietbergen.
Journal of Biomechanics, 45(14):2411-2416, 2012.
BMMB Bone morphology allows estimation of loading history in a murine model of bone adaptation.
P. Christen, B. van Rietbergen, F. M. Lambers, R. Müller, and K. Ito.
Biomechanics and Modeling in Mechanobiology, 11(3-4):483-492, 2012.
Awards
  1. Pre-ORS Best Overall Presentation Award, 18th Annual Symposium on Computational Methods in Orthopaedic Biomechanics, New Orleans, Louisiana, USA, 2010.
  2. IBDW Young Investigator Travel Award, 20th International Bone Densitometry Workshop (IBDW), Hong Kong, China, 2014.
  3. ASBMR John Haddad Young Investigator Award, 30th Advances in Mineral Metabolism (AIMM) / American Society for Bone and Mineral Research (ASBMR) John Haddad Young Investigators' Meeting, Snowmass, Colorado, USA, 2015.
  4. CMBBE Travel Award, 13th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE), Montreal, Canada, 2015.
  5. Finalist ESB Clinical Biomechanics Award, 22st Congress of the European Society of Biomechanics (ESB), Lyon, France, 2016.
Invited Talks
  1. P. Christen. In silico multiscale simulations of bone remodelling in health, disease and treatment. Invited Speaker, 20th International Bone Densitometry Workshop (IBDW 2014), Hong Kong, China, 13-17 October, 2014
  2. P. Christen. In silico multiscale simulations of bone remodelling in health, disease and treatment. Invited Speaker, Fifth Symposium of Academic Exchange and Collaborativ Research between ETH Zurich and Graduate School of Enineering Hokkaido University (AECoR5), Zurich, Switzerland, 27-28 November, 2014.
  3. P. Christen. Quantifying and predicting the mechanoregulation of bone tissue remodelling. Invited Speaker and Session Chair, Young Researcher Minisymposia: Mechano-regulated growth and remodeling in biological tissues. International Association of Applied Mathematics and Mechanics (GAMM) 87th Annual Scientific Conference, Braunschweig, Germany, 7-11 March, 2016.
  4. P. Christen. Computational physiology: Enabling personalised medicine beyond the genome. Invited Speaker, MouseAGE Meeting: Developing interventions for frailty: what do we measure? Vienna, Austria, 14-15 November, 2016.
  5. P. Christen. Personalised medicine and vibration therapy: Computer modelling of mechanical and molecular regulation of bone remodelling. Invited Speaker, 5th ISMST-Basic Research Meeting "Physical Tissue Stimulation: a path to self-healing", Bologna, Italy, 28-29 June, 2018.
  6. P. Christen. Programming. Invited Speaker, Open Day FHNW Business Information Technology, Brugg-Windisch, Switzerland, 17 November, 2018.
  7. P. Christen. Programming. Invited Speaker, Open Day FHNW Business Information Technology, Basel, Switzerland, 23 February, 2019.
Conference Proceedings
  1. P. Christen, S. J. Ferguson, and S. Chegini. Contact mechanics of a discrete fiber-reinforced cartilage model. IV International Conference on Computational Bioengineering (ICCB), Bertinoro (Forli), Italy, 16-18 September, ISSN 2036-9247, p. 58, 2009.
  2. P. Christen, B. van Rietbergen, F. M. Lambers, R. Müller, and K. Ito. Determination of physiological external loading conditions based on bone morphology. 18th Annual Symposium on Computational Methods in Orthopaedic Biomechanics, New Orleans, Louisiana, USA, 5 March, 2010.
  3. P. Christen, B. van Rietbergen, F. M. Lambers, R. Müller, and K. Ito. Determination of physiological external loading conditions based on bone morphology. 56th Annual Meeting of the Orthopaedic Research Society (ORS), New Orleans, Louisiana, USA, 6-9 March, 35:659, 2010.
  4. P. Christen, B. van Rietbergen, F. M. Lambers, R. Müller, and K. Ito. Determination of physiological external loading conditions based on bone morphology. 17th Congress of the European Society of Biomechanics (ESB), Edinburgh, UK, 5-8 July, 509, 2010.
  5. P. Christen, B. van Rietbergen, F. M. Lambers, R. Müller, and K. Ito. Morphology-based bone loading estimation. 20th Annual Meeting of the Dutch Society for Calcium and Bone Metabolism (NVCB), Zeist, The Netherlands, 11-12 November, 2010.
  6. P. Christen, G. Armbrecht, G. Beller, D. Felsenberg, K. Ito, and B. van Rietbergen. Bone strength loss during long-term bed rest is related to bone loading history. 57th Annual Meeting of the Orthopaedic Research Society (ORS), Long Beach, California, USA, 13-16 January, 36:2257, 2011.
  7. P. Christen, B. van Rietbergen, F. M. Lambers, R. Müller, and K. Ito. Morphology-based bone loading estimation. 3rd Dutch Conference on Bio-Medical Engineering, Egmond aan Zee, The Netherlands, 20-21 January, 232, 2011.
  8. P. Christen, B. van Rietbergen, R. Müller, M. R. Rubin, D. W. Dempster, J. P. Bilezikian, and K. Ito. Altered mechanosensitivity can explain the substantially increased bone mass in hypoparathyroidism. ASME 2011 Summer Bioengineering Conference, Farmington, Pennsylvania, USA, 22-25 June, SBC2011-53485, 2011.
  9. P. Christen, I. Knippels, R. Müller, G. H. Lenthe, K. Ito, and B. van Rietbergen. Bone loading estimation in the human distal radius. 58th Annual Meeting of the Orthopaedic Research Society (ORS), San Francisco, California, USA, 4-7 February, 37:374, 2012.
  10. P. Christen, B. van Rietbergen, R. Müller, M. R. Rubin, D. W. Dempster, J. P. Bilezikian, and K. Ito. Altered mechanosensitivity can explain the substantially increased bone mass in hypoparathyroidism. 58th Annual Meeting of the Orthopaedic Research Society (ORS), San Francisco, California, USA, 4-7 February, 37:1535, 2012.
  11. P. Christen, A. A. dos Santos, B. van Rietbergen, R. Müller, and K. Ito. Validation of a bone loading estimation algorithm for patient-specific bone remodeling simulations. 18th Congress of the European Society of Biomechanics (ESB), Lisbon, Portugal, 1-4 July, 1313, 2012.
  12. P. Christen, B. van Rietbergen, I. Knippels, R. Müller, G. H. van Lenthe, and K. Ito. Determination of physiological loading conditions at the human distal radius. 18th Congress of the European Society of Biomechanics (ESB), Lisbon, Portugal, 1-4 July, 1311, 2012.
  13. B. van Rietbergen, P. Christen, M. Colloca, and K. Ito. Toward a patient-specific simulation of bone remodeling. 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS), Vienna, Austria, 10-14 September, 2745, 2012.
  14. P. Christen, R. Ellouz, S. Boutroy, R. Chapurlat, K. Ito, and B. van Rietbergen. Local changes due to bone remodelling are triggered by mechanical loading. Annual Meeting of the American Society for Bone and Mineral Research (ASBMR), Minneapolis, Minnesota, USA, 12-15 October, SA0071, 2012.
  15. M. Colloca, R. Blanchard, P. Christen, C. Hellmich, K. Ito, and B. van Rietbergen. A multiscale approach to describe changes in bone volume fraction due to bone remodeling at the cell level. 59th Annual Meeting of the Orthopaedic Research Society (ORS), San Antonio, Texas, USA, 26-29 January, 38:1489, 2013.
  16. P. Christen, K. Ito, R. Ellouz, S. Boutroy, R. Chapurlat, and B. van Rietbergen. Revealing load-adaptive remodelling in human bone. 59th Annual Meeting of the Orthopaedic Research Society (ORS), San Antonio, Texas, USA, 26-29 January, 38:0345, 2013.
  17. P. Christen, K. Ito, R. Ellouz, S. Boutroy, E. Sornay-Rendu, R. Chapurlat, and B. van Rietbergen. On Wolff's Law in human bone. V International Conference on Computational Bioengineering (ICCB), Leuven, Belgium, 11-13 September, C0012, 2013.
  18. R. Ellouz, R. Chapurlat, B. van Rietbergen, P. Christen, P. Szulc, E. Sornay-Rendu, and S. Boutroy. In vivo local bone remodeling assessed by High Resolution pQCT. 22nd Annual Meeting of the European Orthopaedic Research Society (EORS), Nantes, France, 2-4 July, O19.10, 2014.
  19. P. Christen, S. M. Walker, and G. K. Taylor. Microtomographic reconstruction of the haltere kinematics of the blowfly. 7th World Congress of Biomechanics (WCB), Boston, Massachusetts, USA, 6-11 July, R29, 2014.
  20. S. D. Badilatti, P. Christen, A. Levchuk, I. Parkinson, and R. Müller. Towards simulation of whole bone microstructure adaptation. 7th World Congress of Biomechanics (WCB), Boston, Massachusetts, USA, 6-11 July, M120, 2014.
  21. P. Christen, F. A. Schulte, A. Zwahlen, B. van Rietbergen, L. J. Melton III, S. Amin, S. Khosla, J. Goldhahn, and R. Müller. Reverse engineering estimation of in vivo bone loading history. 20th International Bone Densitometry Workshop (IBDW), Hong Kong, China, 13-17 October, Journal of Orthopaedic Translation, 2:230, 2014.
  22. P. Christen. In silico multiscale simulations of bone remodelling in health, disease and treatment. 5th Symposium on Academic Exchange and Collaborative Research (AECoR-5), Zurich, Switzerland, 27/28 November, p. 14, 2014.
  23. P. Christen. Unravelling the mechanoregulation of bone remodelling in humans. 30th Advances in Mineral Metabolism (AIMM) / American Society for Bone and Mineral Research (ASBMR) John Haddad Young Investigators' Meeting, Snowmass, Colorado, USA, 6-10 April, 2015.
  24. D. Ruffoni, P. Christen, H. Scherf, R. Weinkamer. Wolff's law and the interplay between bone structure and external loading. 4th Joint Meeting of the European Calcified Tissue Society (ECTS) and the International Bone and Mineral Society (IBMS), Rotterdam, The Netherlands, 25-28 April, IBMS BoneKEy, 13:685, p. 14, 2015.
  25. P. Christen, Y. W. W. Lee, B. van Rietbergen, C. Y. J. Cheng, and R. Müller. Time-lapse in vivo image analysis to determine local disease and treatment effects on bone remodelling in patients. 4th Joint Meeting of the European Calcified Tissue Society (ECTS) and the International Bone and Mineral Society (IBMS), Rotterdam, The Netherlands, 25-28 April, IBMS BoneKEy, 13:685, p. 116, 2015.
  26. E. E. Goff, A. Levchuk, A. J. Trüssel, P. Christen, R. Müller. Correlating local strain modalities with local gene expression in vivo in bone tissue. 21st Congress of the European Society of Biomechanics (ESB), Prague, Czech Republic, 5-8 July, 2015.
  27. P. Christen, R. Müller. Image-based computation of in vivo bone loading history in patients. Platform for Advanced Scientific Computing Conference (PASC), Zurich, Switzerland, 2-3 June, 2015.
  28. E. E. Goff, A. Levchuk, A. J. Trüssel, P. Christen, R. Müller. A computational approach to correlate local mechanical tissue loading in bone with local gene expression in vivo. 13th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE), Montreal, Canada, 1-5 September, 2015.
  29. P. Christen, Y. W. W. Lee, B. van Rietbergen, C. Y. J. Cheng, and R. Müller. Image-based computation of local disease and treatment effects on bone remodelling in patients. 13th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE), Montreal, Canada, 1-5 September, 2015.
  30. S. D. Badilatti, P. Christen, S. J. Ferguson, and R. Müller. Simulation of long-term bone adaptation to cement augmentation in whole human vertebrae. Annual Meeting of The Swiss Society for Biomedical Engineering (SSBE), Neuchatel, Switzerland, 26-27 Aug, 2015.
  31. P. Christen. Quantifying and predicting the mechanoregulation of bone tissue remodelling. Joint Annual Meeting of Deutsche Mathematiker-Vereinigung (DMV) and Gesellschaft für Angewandte Mathematik und Mechanik (GAMM), Braunschweig, Germany, 7-11 March, 2016.
  32. P. Christen, and R. Müller. Personalized in silico bone health prognosis. Latsis Symposium ETH Zurich on Personalized Medicine, Zurich, Switzerland, 27-29 June 2016.
  33. N. Ohs, R. Müller, and P. Christen. Personalized in silico prognosis using clinical big data. Latsis Symposium ETH Zurich on Personalized Medicine, Zurich, Switzerland, 27-29 June 2016.
  34. J. A. Steiner, P. Christen, S. J. Ferguson, and G. H. van Lenthe. Towards a patient-specific in silico model to accurately quantify implant primary stability in osteoporotic bone. 22st Congress of the European Society of Biomechanics (ESB), Lyon, France, 10-13 July, 2016.
  35. S. D. Badilatti, P. Christen, I. Parkinson, and R. Müller. In silico simulation of microstructural bone loss in osteoporotic whole human vertebrae. 22st Congress of the European Society of Biomechanics (ESB), Lyon, France, 10-13 July, 2016.
  36. G. Paul, Z. Li, P. Christen, and R. Müller. Effects of implant pin misalignment on tissue loading in murine caudal vertebrae: a computational pilot study. 22st Congress of the European Society of Biomechanics (ESB), Lyon, France, 10-13 July, 2016.
  37. P. Christen, G. Marano, Y.-W. W. Lee, C.-Y. J. Cheng, and R. Müller. Counteracting decreased bone strength in young females with adolescent idiopathic scoliosis. 22st Congress of the European Society of Biomechanics (ESB), Lyon, France, 10-13 July, 2016.
  38. P. Christen. Perspective Talk: In silico bone health prognosis. 22st Congress of the European Society of Biomechanics (ESB), Lyon, France, 10-13 July, 2016.
  39. N. Ohs, F. Keller, O. Blank, W.-Y. W. Lee, C.-Y. J. Cheng, P. Arbenz, R. Müller, and P. Christen. Towards in silico prognosis using big data. Dreiländertagung of the Austrian, German and Swiss Societies for Biomedical Engineering, Basel, Switzerland, 4-6 October 2016. Current Directions in Biomedical Engineering.
  40. G. Marano, Y.-W. W. Lee, T.-P. Lam, R. Müller, and P. Christen. Effects of whole body vibration therapy on bone strength and mechanical tissue loading in the distal tibia of girls with adolescent idiopathic scoliosis. Joint Annual Meeting of The Swiss Association against Osteoporosis (SVGO) and The Swiss Bone and Mineral Society (SBMS), Bern, Switzerland, 4 May, 2017.
  41. A. Scheuren, R. Plett, C. Taylor, P. Christen, and R. Müller. Local in vivo environment (LivE) imaging in bone. International Collaboration on Repair Discoveries (ICORD) Trainee Symposium, Vancouver, Canada, 14 June, 2017.
  42. D. Betts, E. Goff, M. Casanova, Z. Li, P. Christen, and R. Müller. Segmentation of osteocyte lacuna within ultra-high resolution desktop micro-CT images: Sensitivity and precision reveal issues with current state of the art. 21th International Bone Densitometry Workshop (IBDW) and 7th European Symposium on Ultrasonic Characterization of Bone (ESUCB), Banz, Germany, 26-30 June, 2017.
  43. G. Marano, Y.-W. W. Lee, C.-Y. J. Cheng, R. Müler, and P. Christen. Whole body vibration therapy reduces local peak loading in the distal tibia of girls with adolescent idiopathic scoliosis. 21th International Bone Densitometry Workshop (IBDW) and 7th European Symposium on Ultrasonic Characterization of Bone (ESUCB), Banz, Germany, 26-30 June, 2017.
  44. N. Ohs, Y.-W. W. Lee, C.-Y. J. Cheng, R. Müller, and P. Christen. Personalised bone health prognosis through integrated patient big data analysis of medical images, molecular profiles and physical activity levels. 21th International Bone Densitometry Workshop (IBDW) and 7th European Symposium on Ultrasonic Characterization of Bone (ESUCB), Banz, Germany, 26-30 June, 2017.
  45. A. Scheuren, R. Plett, C. Taylor, P. Christen, and R. Müller. Visualisation and analysis of diverse experimental data from 3D local in vivo environment (live) imaging in bone. 23st Congress of the European Society of Biomechanics (ESB), Seville, Spain, 2-5 July, 2017.
  46. E. Goff, D. Betts, P. Christen, and R. Müller. Influence of uCT beam energy on cell lacunar imaging. 23st Congress of the European Society of Biomechanics (ESB), Seville, Spain, 2-5 July, 2017.
  47. A. Scheuren, R. Plett, C. Taylor, P. Christen, and R. Müller. Multiscale 3D data visualization for exploring diverse mechanobiological interactions in bone. Annual Meeting of the Swiss Society for Biomedical Engineering (SSBE), Zurich, Switzerland, 30 August, 2017.
  48. E. Goff, D. C. Betts, Z. Li, M. Casanonva, P. Christen, and R. Müller. Cell lacunar imaging dependence on uCT beam energy. Annual Meeting of the Swiss Society for Biomedical Engineering (SSBE), Zurich, Switzerland, 30 August, 2017.
  49. N. Ohs, J. Kleffmann, Y.-W. W. Lee, C.-Y. J. Cheng, P. Arbenz, R. Müller, and P. Christen. Patient big data - an analysis integrating medical images, molecular profiles and physical activity levels. Annual Meeting of the Swiss Society for Biomedical Engineering (SSBE), Zurich, Switzerland, 30 August, 2017.
  50. P. Christen, N. Ohs, Y.-W. W. Lee, T.-P. Lam, P. Arbenz, and R. Müller. A computational data science framework for personalised bone health prognosis. VII International Conference on Computational Bioengineering (ICCB), Compiègne, France, 6-8 September, 2017.
  51. P. Christen, G. Marano, Y.-W. W. Lee, T.-P. Lam, and R. Müller. Whole body vibration therapy triggers load-driven bone formation in adolescents with idiopathic scoliosis. Annual Meeting of the American Society for Bone and Mineral Research (ASBMR), Denver, Colorado, USA, 8-11 September, 2017.
  52. G. Marano, Y.-W. W. Lee, T.-P. Lam, R. Müller, and P. Christen. Whole body vibration therapy counteracts increasing local peak loading in the distal tibia of girls with adolescent idiopathic scoliosis. The 37th Annual Congress of The Hong Kong Orthopaedic Association (HKOA), Hong Kong, China, 4-5 November, p. 100, 2017.
  53. S. Sebastian, G. Marano, Y.-W. W. Lee, T.-P. Lam, R. Müller, and P. Christen. Potential of whole body vibration therapy to increase bone strength in adolescents with idiopathic scoliosis. Joint Annual Meeting of The Swiss Association against Osteoporosis (SVGO) and The Swiss Bone and Mineral Society (SBMS), Bern, Switzerland, 3 May, 2018.
  54. K. Simon, G. Marano, M. Blauth, R. Arora, R. Müller, and P. Christen. Local in vivo assessment of human distal radius fractures by time-lapse HR-pQCT. Joint Annual Meeting of The Swiss Association against Osteoporosis (SVGO) and The Swiss Bone and Mineral Society (SBMS), Bern, Switzerland, 3 May, 2018.
  55. E. Goff, J. P. McKinley, D. C. Betts, P. Christen, and R. Müller. A novel histogram-based thresholding approach for accurate segmentation of osteocyte lacunae in micro-CT images of human bone biopsies. 8th World Congress of Biomechanics (WCB), Dublin, Ireland, 8-12 July, O0418, 2018.
  56. D. Betts, M. Grass, N. Ohs, A. Malhotra, P. Christen, E. Wehrle, and R. Müller. A three-dimensional multiscale model of fracture healing in mice: Sensitivity of callus microstructure to osteoblast polarization and initial MSC density. 8th World Congress of Biomechanics (WCB), Dublin, Ireland, 8-12 July, O0731, 2018.
  57. N. Ohs, S. Sebastian, B. van Rietbergen, R. Müller, and P. Christen. Voxel size dependency of a load-adaptive bone remodelling algorithm. 8th World Congress of Biomechanics (WCB), Dublin, Ireland, 8-12 July, O0583, 2018.
  58. F. Keller and P. Christen. Bone as a complex system: Computing bone remodelling across biological hierarchies. 8th World Congress of Biomechanics (WCB), Dublin, Ireland, 8-12 July, O1389, 2018.
  59. E. Goff, J. P. McKinley, D. C. Betts, P. Christen, Carmen Eskesen, and R. Müller. A predictive histogram-based thresholding approach for micro-CT segmenting human osteocyte lacunae. Annual Meeting of the Swiss Society for Biomedical Engineering (SSBE), Biel, Switzerland, 28 August, 2018.
  60. K. Simon, M. Blauth, G. Degenhart, R. Müller, P. Christen, and R. Arora. In vivo Untersuchungsprotokoll mittels HR-pQCT erlaubt detailgetreue Beurteilung der knöchernen Heilung bei distalen Radiusfrakturen. 54. Jahrestagung der Österreichischen Gesellschaft für Unfallchirurgie, Salzburg, Austria, 4-6 October, 2018.
  61. N. Ohs, D. Betts, S. Sebastian, B. van Rietbergen, R. Müller, and P. Christen. Virtual high-resolution reduces voxel size effects of a load-adaptive bone remodeling algorithm. 22nd International Workshop on Quantitative Musculoskeletal Imaging (QMSKI), Lake Louise, Alberta, Canada, 24 February - 1 March, 2019.
  62. L. Engelhardt, M. Melzner, L. Havelkova, P. Fiala, P. Christen, S. Dendorfer, U. Simon. A new musculoskeletal AnybodyTM detailed hand model. 25th Congress of the European Society of Biomechanics (ESB), Vienna, Austria, 7-10 July, 2019.
  63. L. Engelhardt, F. Niemeyer, T. Seger, L. Zanotti, P. Christen, R. Müller, K. Simon, M. Blauth, A. Ignatius, U. Simon. Computational healing simulation of compression fractures in the distal radius. 25th Congress of the European Society of Biomechanics (ESB), Vienna, Austria, 7-10 July, 2019.
  64. P. Atkins, K. Simon, N. Ohs, P. Christen, M. Blauth, and R. Müller. In vivo motion artifacts significantly degrade image registration accuracy. 25th Congress of the European Society of Biomechanics (ESB), Vienna, Austria, 7-10 July, 2019.
  65. N. Ohs, D. C. Betts, C. M. O’Neill, C. Eskesen, R. Müller, and P. Christen. Fully automated contouring of HR-pQCT images of distal radius fractures. 25th Congress of the European Society of Biomechanics (ESB), Vienna, Austria, 7-10 July, 2019.
  66. C. Collins, N. Ohs, P. Atkins, L. Horling, M. Blauth, R. Müller, and P. Christen. Delayed fracture healing detected in aged distal radius fracture patients using in vivo HR-pQCT-based micro-FEA. 25th Congress of the European Society of Biomechanics (ESB), Vienna, Austria, 7-10 July, 2019.
  67. P. Christen, and O. Del Fabbro. Cybernetical Concepts for Cellular Automaton and Artificial Neural Network Modelling and Implementation. IEEE International Conference on Systems, Man, and Cybernetics, Bari, Italy, 6-9 October, 2019. Accepted.
Monographs
PhD Thesis Deciphering the secret message within bone microstructure.
PhD Thesis, Eindhoven University of Technology, ISBN 978-90-386-3323-7, 2013.
P. Christen.
MSc Thesis Contact mechanics of a discrete fiber-reinforced cartilage model.
MSc Thesis, University of Bern, 2009.
P. Christen.